Cannabis Dependence

8K2914

Cannabis dependence reflects a pattern of repeated use that becomes hard to control—where the line between casual and compulsive blurs, often tied to cravings, tolerance, and withdrawal symptoms. Research shows that variations near genes involved in endocannabinoid signaling and neural reward pathways (like CNR1, CADM...

SNP Stats

Mapeados
29
Positivos
12 (41.4%)
Negativos
17 (58.6%)

Genome Matching (1)

Resultados Públicos (7.973)

Traços Conectados (1)

cannabis dependence

EFO_0007191

0 evidências30 SNPs1 traços0 estudos0 positivos · 0 negativos

Estudos Conectados (4)

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.

PubMed 37985822

0 evidências26 SNPs1 traços1 estudos0 positivos · 0 negativos

Genome-wide association study identifies a novel locus for cannabis dependence.

PubMed 29112194

0 evidências8 SNPs2 traços1 estudos0 positivos · 0 negativos

A large-scale genome-wide association study meta-analysis of cannabis use disorder.

PubMed 33096046

0 evidências2 SNPs1 traços1 estudos0 positivos · 0 negativos

Genes Conectados (21)

CADM2

cell adhesion molecule 2

This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like d...

1 evidências319 SNPs0 traços0 estudos0 positivos · 1 negativos

PDE4B

phosphodiesterase 4B

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of...

1 evidências204 SNPs0 traços0 estudos1 positivos · 0 negativos

SEMA6D

semaphorin 6D

Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding...

1 evidências179 SNPs0 traços0 estudos0 positivos · 1 negativos

ERC2

ELKS/RAB6-interacting/CAST family member 2

This gene encodes a protein that belongs to the Rab3-interacting molecule (RIM)-binding protein family. Members of this protein family form part of the cytomatrix at the active...

1 evidências138 SNPs0 traços0 estudos1 positivos · 0 negativos

MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2

The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian at...

1 evidências133 SNPs0 traços0 estudos1 positivos · 0 negativos

SNPs Conectados (29)

rs4702

FURIN

chr15additiveAlt A1.000

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