cannabis dependence
EFO_0007191
0 evidence30 SNPs1 traits0 studies0 positive · 0 negative
Cannabis Dependence
8K2914
Cannabis dependence reflects a pattern of repeated use that becomes hard to control—where the line between casual and compulsive blurs, often tied to cravings, tolerance, and withdrawal symptoms. Research shows that variations near genes involved in endocannabinoid signaling and neural reward pathways (like CNR1, CADM...
SNP Stats
- Mapped
- 29
- Positive
- 12 (41.4%)
- Negative
- 17 (58.6%)
Genome Matching (1)
Public Results (7,973)
5714.4189
OpenSNP · European · Human
4 of 29 SNPs with zeta at 7.034
9674.7945
OpenSNP · European · Human
4 of 29 SNPs with zeta at 7.034
9865.8121
OpenSNP · European American · Human
4 of 29 SNPs with zeta at 7.034
5673.4158
OpenSNP · European American · Human
4 of 29 SNPs with zeta at 7.034
5568.4058
OpenSNP · European American · Human
4 of 29 SNPs with zeta at 7.034
5402.3915
OpenSNP · European American · Human
4 of 29 SNPs with zeta at 7.034
4529.3126
OpenSNP · European · Human
4 of 29 SNPs with zeta at 7.034
Connected Traits (1)
Connected Studies (4)
Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.
0 evidence26 SNPs1 traits1 studies0 positive · 0 negative
Genome-wide association study identifies a novel locus for cannabis dependence.
0 evidence8 SNPs2 traits1 studies0 positive · 0 negative
A large-scale genome-wide association study meta-analysis of cannabis use disorder.
0 evidence2 SNPs1 traits1 studies0 positive · 0 negative
Connected Genes (21)
CADM2
cell adhesion molecule 2
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like d...
1 evidence319 SNPs0 traits0 studies0 positive · 1 negative
PDE4B
phosphodiesterase 4B
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of...
1 evidence204 SNPs0 traits0 studies1 positive · 0 negative
SEMA6D
semaphorin 6D
Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding...
1 evidence179 SNPs0 traits0 studies0 positive · 1 negative
ERC2
ELKS/RAB6-interacting/CAST family member 2
This gene encodes a protein that belongs to the Rab3-interacting molecule (RIM)-binding protein family. Members of this protein family form part of the cytomatrix at the active...
1 evidence138 SNPs0 traits0 studies1 positive · 0 negative
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian at...
1 evidence133 SNPs0 traits0 studies1 positive · 0 negative