restless legs syndrome
EFO_0004270
0 evidências399 SNPs1 traços0 estudos0 positivos · 0 negativos
Restless Legs
8K383110
Restless Legs Syndrome (RLS) is a neurological condition characterized by an uncontrollable urge to move the legs, often accompanied by uncomfortable sensations, especially during periods of rest or at night. Research shows that variations near genes involved in dopamine signaling and iron metabolism (like MEIS1, BTBD...
SNP Stats
- Mapeados
- 383
- Positivos
- 203 (53.0%)
- Negativos
- 180 (47.0%)
Genome Matching (1)
Resultados Públicos (7.972)
NA11992
1000 Genomes Project · European · Human
347 de 368 SNPs com zeta em 5.228
NA18564
1000 Genomes Project · East Asian · Human
347 de 368 SNPs com zeta em 4.687
HG04131
1000 Genomes Project · South Asian · Human
347 de 368 SNPs com zeta em 4.559
HG03884
1000 Genomes Project · South Asian · Human
347 de 368 SNPs com zeta em 4.385
NA18991
1000 Genomes Project · East Asian · Human
347 de 368 SNPs com zeta em 4.190
NA18967
1000 Genomes Project · East Asian · Human
347 de 368 SNPs com zeta em 4.182
huDA2757
Personal Genome Project · European American · Human
188 de 368 SNPs com zeta em 4.166
Traços Conectados (1)
Estudos Conectados (10)
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.
0 evidências15K SNPs829 traços1 estudos0 positivos · 0 negativos
Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction.
0 evidências331 SNPs1 traços1 estudos0 positivos · 0 negativos
Large genome-wide association study identifies three novel risk variants for restless legs syndrome.
0 evidências25 SNPs1 traços1 estudos0 positivos · 0 negativos
Genes Conectados (152)
POLR1HASP
POLR1H antisense, pseudogene
1 evidências367 SNPs0 traços0 estudos1 positivos · 0 negativos
PTPRD
protein tyrosine phosphatase receptor type D
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular proce...
16 evidências283 SNPs0 traços0 estudos9 positivos · 7 negativos
DAB1
DAB adaptor protein 1
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain...
7 evidências249 SNPs0 traços0 estudos3 positivos · 4 negativos
ASTN2
astrotactin 2
This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mou...
1 evidências212 SNPs0 traços0 estudos0 positivos · 1 negativos
CTNNA3
catenin alpha 3
This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are...
1 evidências208 SNPs0 traços0 estudos0 positivos · 1 negativos