Age at Menopause

8K20919

Menopause marks a profound biological transition in a woman’s life—often signifying both an ending and a beginning. Though frequently framed as a source of loss, this phase can also usher in clarity, autonomy, and freedom from certain social or physiological burdens. While the age at which it begins varies, it tends to...

SNP Stats

Mapped
209
Positive
117 (56.0%)
Negative
92 (44.0%)

Genome Matching (1)

Public Results (7,972)

Connected Traits (1)

age at menopause

EFO_0004704

0 evidence215 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (9)

Genetic insights into biological mechanisms governing human ovarian ageing.

PubMed 34349265

0 evidence57 SNPs1 traits1 studies0 positive · 0 negative

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

PubMed 26414677

0 evidence53 SNPs1 traits1 studies0 positive · 0 negative

Joint genome-wide association analyses identified 49 novel loci for age at natural menopause.

PubMed 34050765

0 evidence52 SNPs1 traits1 studies0 positive · 0 negative

Connected Genes (137)

HLA-F-AS1

HLA-F antisense RNA 1

1 evidence512 SNPs0 traits0 studies1 positive · 0 negative

MIR4435-2HG

MIR4435-2 host gene

1 evidence207 SNPs0 traits0 studies0 positive · 1 negative

LSAMP

limbic system associated membrane protein

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neu...

1 evidence203 SNPs0 traits0 studies0 positive · 1 negative

BABAM2

BRISC and BRCA1 A complex member 2

This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several pr...

2 evidence152 SNPs0 traits0 studies0 positive · 2 negative

LINC01505

long intergenic non-protein coding RNA 1505

1 evidence147 SNPs0 traits0 studies1 positive · 0 negative

Connected SNPs (209)

rs4246511

RHBDL2, RRAGC-DT

chr1additiveAlt C1.000

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