Open phenotype catalog


Browse public phenotypes.

Explore the Genodex public phenotype catalog and preview public result context from public genomes.

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Showing 1-30 of 120 public phenotypes

Cognitive Function Measurement

Cognitive function measurement captures how well your brain performs tasks like memory, reasoning, attention, and problem-solving — core abilities that shape learning and daily decision-making. Research shows that variations near genes involved in synaptic plasticity, neurotransmission, and brain development (such as COMT, BDNF, and APOE) can influence individual differences in cognitive performance. Cognitive abilities vary widely across the population, with heritability estimates ranging from 50–80%, reflecting a strong genetic component alongside environmental factors like education and lifestyle.

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Eye Color

Eye color is your visible genetic signature — determined by the amount and type of pigments in the iris, giving rise to shades from blue and green to brown and hazel. Research shows that variations near genes involved in melanin production and iris development (like OCA2, HERC2, and TYR) play a major role in determining eye color. Eye color distribution varies globally, with high heritability estimates often above 90%, making it one of the most strongly genetically determined human traits.

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Hair Color

Hair color is a visible genetic trait determined by the type and amount of melanin pigment in your hair, resulting in a range of shades from black and brown to blonde and red. Research shows that variations near genes involved in pigmentation (like MC1R, OCA2, and TYRP1) play a major role in determining hair color diversity. Hair color has high heritability — often above 80% — making it one of the most strongly genetically influenced physical traits.

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Skin Pigmentation

Our skin tone is a visible echo of our ancestors’ environments. It’s not about beauty standards — it’s about biology, adaptation, and survival. From equatorial sun to northern twilight, human skin has evolved to strike a balance between protection from UV radiation and production of vitamin D. Embracing this diversity isn’t just respectful — it’s scientifically profound. Skin pigmentation is primarily controlled by genes like MC1R, SLC24A5, OCA2, and TYR, which influence melanin production, type, and distribution within the skin. The heritability of skin pigmentation is exceptionally high, ranging from 70% to 90% across populations. Variants in SLC24A5 alone explain up to 25–38% of pigmentation differences between major continental groups.

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Aggressive Behavior Quality

Aggressive behavior quality reflects the intensity, frequency, and control of aggressive responses—ranging from occasional assertiveness to patterns of hostility that affect relationships and wellbeing. Understanding these variations helps us appreciate how biology and experience shape emotional regulation and social interactions. Genetic influences on aggressive behavior quality involve variants near genes like MAOA, COMT, and SLC6A4, which regulate neurotransmitters such as serotonin and dopamine, key to mood and impulse control. Heritability estimates for aggressive behavior quality typically range from 40% to 60%, emphasizing the significant genetic contribution alongside environmental factors like childhood experiences and social environment.

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Alcohol Drinking

Alcohol drinking is your social ritual turned measurable habit—whether it’s a glass of wine with dinner or a weekend night out, it reflects a blend of culture, personal choice, and biology. Research shows that variations near genes regulating alcohol metabolism (like ADH1B and ALDH2) and those influencing reward pathways (such as GABRA2) can shape individual differences in drinking behavior. Worldwide, about 43% of adults report current alcohol use, and twin studies estimate heritability of general alcohol consumption at around 40–60%, highlighting a significant genetic influence on how much—and how often—you drink.

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Attention Function Measurement

Attention function measurement is your brain’s built‑in spotlight on the world, gauging how sharply you focus on a task or filter out distractions—whether reading a book in a noisy cafĂ© or zoning back into work after an interruption. Research shows that variations near genes regulating dopamine signaling and fronto‑striatal circuitry (like DRD4, COMT, and SLC6A3) can influence individual differences in sustained attention and distractibility. While clinically significant attention deficits (such as those seen in ADHD) affect about 5% of children, continuous measures of attention performance span the entire population—and twin studies estimate heritability of general attentional capacity at roughly 70–80%, underscoring a strong genetic contribution.

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Behavioral Disinhibition Measurement

Behavioral disinhibition measurement is your mind’s built‑in impulse gauge, tracking how often you act without thinking—from blurting out comments to chasing thrills—revealing when self‑control takes a back seat to spontaneity. Research shows that variations near genes regulating inhibitory neurotransmission (like GABRA2 and CHRNA5) and those affecting dopamine signaling pathways (such as DRD2) can shape individual differences in disinhibitory behavior. While extreme disinhibition underlies conditions like ADHD or substance‐use disorders (affecting roughly 5–10% of people), trait‐level measures span the entire population, and twin studies estimate heritability of general disinhibition at around 50–60%, highlighting a significant genetic contribution.

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Body Fat Percentage

Body fat percentage is your body’s hidden dashboard for the balance between lean tissue and stored energy—revealing whether you carry more muscle or extra padding, and offering a clearer picture of health than weight alone. Research shows that variations near genes regulating adipogenesis and energy balance (like FTO and PPARG) and those influencing lipid storage and mobilization (such as ADIPOQ) can shape individual differences in how much body fat you carry. In healthy adults, average body fat percentage ranges roughly from 10–20% in men and 20–30% in women, and twin studies estimate heritability at about 40–60%, highlighting a substantial genetic role in determining your body’s composition.

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Body Height

Body height is your most visible genetic signature — shaped early in life and standing tall as a reflection of bone growth, nutrition, and inherited growth potential. Research shows that variations near genes involved in skeletal development and growth hormone pathways (like HMGA2, EFEMP1, and GDF5) can strongly influence final adult stature. Height is one of the most heritable human traits, with genetic factors accounting for approximately 80–90% of variation, and average adult height ranging globally from about 160 cm to 180 cm depending on population and sex.

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Brain Connectivity Attribute

Brain connectivity attribute is your neural network’s blueprint—capturing how different regions of the brain communicate, sync, and relay information, shaping everything from memory to emotion to decision‑making. Research shows that variations near genes involved in synaptic structure and signaling (like CNTNAP2, DISC1, and NRXN1) can influence patterns of functional and structural brain connectivity. Individual differences in brain connectivity are measurable through imaging techniques like fMRI or DTI, and twin studies estimate heritability between 40–60%, highlighting a significant genetic role in shaping how your brain is wired.

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Brain Volume

Brain volume is your brain’s physical footprint—measuring the total size of the organ that governs thought, emotion, and behavior, and offering clues about development, aging, and neurological health. Research shows that variations near genes involved in neurodevelopment and cell growth (like HMGA2, MAPT, and KIAA0586) can influence total brain volume as well as specific regional sizes. Average adult brain volume is about 1,200–1,500 cm³, and heritability estimates range from 70–90%, making it one of the most strongly genetically influenced traits in human biology.

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Breastfeeding Duration

Breastfeeding duration reflects a complex interplay of biology, behavior, and context—capturing how long a mother continues nursing, shaped by milk supply, infant needs, cultural norms, and personal choice. Research shows that variations near genes involved in prolactin signaling, lactation physiology, and hormonal regulation (like OXTR, PRL, and ESR1) can influence the ability and duration of breastfeeding. Breastfeeding duration varies widely across populations, with global averages ranging from a few weeks to over a year, and heritability estimates from twin studies falling between 40–60%, indicating a moderate genetic influence alongside strong social and environmental factors.

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Cannabis Use

Cannabis use is a behavioral trait capturing whether—and how often—someone consumes cannabis, shaped by social context, personal preference, and neurobiological sensitivity. Research shows that variations near genes involved in reward processing, impulse control, and cannabinoid signaling (like CADM2, NCAM1, and CNR1) can influence likelihood and frequency of cannabis use. Lifetime cannabis use is reported by 20–40% of adults in many countries, with heritability estimates ranging from 40–60%, indicating a notable genetic influence alongside strong environmental and cultural factors.

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Creativity Measurement

Creativity measurement captures your brain’s ability to generate novel ideas, solve problems in unique ways, and think outside the box—fueling innovation, art, and everyday imagination. Research shows that variations near genes involved in dopamine signaling, synaptic plasticity, and cognitive flexibility (such as DRD2, BDNF, and COMT) can influence individual differences in creative thinking. Creativity varies widely among individuals, with heritability estimates ranging from 30–50%, indicating both genetic and environmental factors contribute to creative potential.

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Daytime Rest Measurement

Daytime rest measurement captures how often and how long you take breaks or naps during the day—reflecting your body’s need to recharge and maintain alertness. Research shows that variations near genes regulating sleep‑wake cycles and circadian rhythms (like PER3, CLOCK, and ABCC9) can influence individual differences in daytime rest patterns. Daytime napping habits vary widely across cultures and individuals, with heritability estimates around 30–50%, highlighting a moderate genetic influence alongside lifestyle and environmental factors.

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Energy Intake

Energy intake measures the amount of calories consumed through food and drink—fueling your body’s daily activities, metabolism, and overall energy balance. Research shows that variations near genes regulating appetite, metabolism, and satiety (like FTO, MC4R, and LEPR) can influence individual differences in energy consumption. Daily energy intake varies widely based on age, sex, and lifestyle, with heritability estimates around 40–60%, highlighting a notable genetic contribution alongside environmental factors.

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Facial Wrinkling

Facial wrinkling is your skin’s natural record of aging and environmental exposure, showing lines and creases formed by years of repeated expressions, sun damage, and collagen breakdown. Research shows that variations near genes involved in skin elasticity and collagen production (like MMP1, ELN, and COL1A1) can influence the extent and pattern of facial wrinkles. Wrinkling increases with age for everyone, but heritability estimates range from 30–50%, indicating that genetics plays a moderate role alongside lifestyle factors like sun exposure and smoking.

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Feeling Miserable Measurement

Feeling miserable measurement captures the intensity and frequency of low mood or unhappiness—reflecting how individuals experience and process feelings of sadness, frustration, or dissatisfaction. Research shows that variations near genes involved in mood regulation and neurotransmitter systems (such as SLC6A4, BDNF, and CRHR1) can influence susceptibility to persistent negative emotions. Prevalence of significant low mood varies, with heritability estimates around 30–50%, indicating that both genetic and environmental factors contribute to the experience of feeling miserable.

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Feeling Nervous Measurement

Feeling nervous measurement captures how often and intensely individuals experience feelings of unease, worry, or anxiety—common emotional responses to stress or uncertain situations. Research shows that variations near genes involved in the stress response and neurotransmission (like CRHR1, SLC6A4, and GABRA2) can influence individual differences in nervousness and anxiety levels. Nervousness varies widely across people, with heritability estimates around 30–50%, highlighting the combined role of genetics and environment in shaping this emotional trait.

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Feeling Tense Measurement

Feeling tense measurement captures how frequently and intensely individuals experience physical and mental stiffness or stress—often manifesting as muscle tightness, restlessness, or irritability during challenging situations. Research shows that variations near genes involved in stress regulation and neurotransmitter activity (such as CRHR1, SLC6A4, and GABRA2) can influence individual differences in tension and stress response. Tension levels vary widely across individuals, with heritability estimates around 30–50%, reflecting a blend of genetic predisposition and environmental influences like stress and lifestyle.

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Fish Consumption

Fish consumption measures how often and how much fish an individual eats—a dietary habit linked to heart health, brain function, and nutrient intake like omega-3 fatty acids. Research shows that variations near genes influencing taste preference, lipid metabolism, and dietary habits (such as FADS1, FADS2, and CYP2A6) can affect individual differences in fish consumption. Fish consumption varies widely across populations and cultures, with heritability estimates around 30–50%, highlighting genetic and environmental factors shaping dietary choices.

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Freckles

Freckles are small, concentrated spots of melanin on the skin, often appearing on sun-exposed areas and becoming more prominent with sunlight exposure. Research shows that variations near genes involved in pigmentation regulation (like MC1R, TYR, and ASIP) strongly influence freckle formation and distribution. Freckles are more common in individuals with lighter skin tones, and heritability estimates are high—often above 80%—making freckles a strongly genetically determined trait.

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Guilt Measurement

Guilt measurement captures how strongly and frequently individuals experience feelings of remorse or responsibility after actions perceived as wrong—playing a key role in social behavior and moral development. Research shows that variations near genes involved in emotional regulation and social cognition (such as OXTR, SLC6A4, and MAOA) can influence individual differences in guilt sensitivity. Guilt sensitivity varies among individuals, with heritability estimates around 30–50%, reflecting a combination of genetic predisposition and environmental factors like upbringing and cultural norms.

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Height Growth Attribute

Height growth attribute measures the rate at which an individual’s stature increases over time—reflecting how quickly bones lengthen during childhood and adolescence. Research shows that variations near genes involved in skeletal growth and hormone regulation (like FGFR3, IGF1, and GHR) can influence differences in growth velocity. Growth rates vary widely among individuals, with heritability estimates around 60–80%, underscoring a strong genetic influence on how rapidly height increases during development.

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Insomnia

Insomnia is the difficulty falling or staying asleep, leading to poor sleep quality and daytime fatigue—often triggered by stress, lifestyle, or underlying health conditions. Research shows that variations near genes involved in circadian rhythm regulation and neurotransmission (like ABCC9, PER3, and GRIA2) can influence susceptibility to insomnia. Insomnia affects about 10–30% of adults worldwide, with heritability estimates around 30–40%, highlighting a moderate genetic contribution alongside environmental and behavioral factors.

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Intelligence

Intelligence captures your brain’s overall capacity for learning, reasoning, problem-solving, and adapting to new situations—core skills shaping everyday life and complex tasks alike. Research shows that variations near genes involved in brain development, synaptic function, and neurotransmission (such as FOXP2, BDNF, and COMT) can influence individual differences in intelligence. Intelligence varies widely across the population, with heritability estimates ranging from 50–80%, reflecting a strong genetic influence alongside environmental factors like education and socioeconomic status.

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Irritability Measurement

Irritability measurement captures how easily and frequently an individual becomes annoyed or frustrated—reflecting emotional sensitivity to stress, discomfort, or social interactions. Research shows that variations near genes involved in emotional regulation and neurotransmitter function (such as SLC6A4, MAOA, and COMT) can influence individual differences in irritability. Irritability levels vary across individuals, with heritability estimates around 30–50%, highlighting a combination of genetic predisposition and environmental influences like stress and lifestyle.

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Mathematical Ability

Mathematical ability measures your capacity to understand, reason with, and solve numerical problems—skills essential for logic, calculation, and analytical thinking. Research shows that variations near genes involved in cognitive processing and brain development (like ROBO1, FOXP2, and KIAA0319) can influence individual differences in mathematical skills. Mathematical ability varies widely among individuals, with heritability estimates ranging from 40–60%, reflecting a significant genetic influence alongside educational and environmental factors.

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Memory Performance

Memory performance captures how effectively you can encode, store, and retrieve information—shaping everything from daily recall to long-term learning. Research shows that variations near genes involved in synaptic plasticity and neural signaling (such as BDNF, APOE, and COMT) can influence individual differences in memory ability. Memory capacity varies widely among individuals, with heritability estimates ranging from 40–70%, highlighting a strong genetic contribution alongside environmental influences like education and health.

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