Astigmatism

8K8715

Astigmatism is your eye’s personal curveball—a subtle distortion in the way light bends across the cornea or lens, turning once-crisp edges into gentle blurs or light streaks. It’s a reminder that even our most routine moments—reading a book or gazing out a window—rely on the precise geometry of our eyes, and when that...

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SNP Stats

Mapped
86
Positive
55 (64.0%)
Negative
31 (36.0%)

Genome Matching (1)

Public Results (7,970)

4623.3224

OpenSNP · East Asian · Human

22 of 86 SNPs with zeta at 5.598

99.9

4427.3033

OpenSNP · American South Asian · Human

21 of 86 SNPs with zeta at 5.473

99.9

5899.4380

OpenSNP · European American · Human

22 of 86 SNPs with zeta at 5.082

99.9

9687.7955

OpenSNP · European · Human

20 of 86 SNPs with zeta at 5.037

99.9

8997.7340

OpenSNP · European · Human

20 of 86 SNPs with zeta at 5.037

99.9

8003.6341

OpenSNP · European · Human

20 of 86 SNPs with zeta at 5.037

99.9

9740.7998

OpenSNP · European · Human

28 of 86 SNPs with zeta at 4.891

99.9

Connected Traits (1)

astigmatism

HP_0000483

0 evidence87 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (5)

Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci.

PubMed 30306274

0 evidence85 SNPs2 traits1 studies0 positive · 0 negative

Identification of a candidate gene for astigmatism.

PubMed 23322567

0 evidence16 SNPs1 traits1 studies0 positive · 0 negative

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.

PubMed 25367360

0 evidence15 SNPs1 traits1 studies0 positive · 0 negative

Connected Genes (50)

RBFOX1

RNA binding fox-1 homolog 1

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regul...

1 evidence409 SNPs0 traits0 studies1 positive · 0 negative

CDH13

cadherin 13

This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a tr...

1 evidence226 SNPs0 traits0 studies0 positive · 1 negative

LYPLAL1-AS1

LYPLAL1 antisense RNA 1

1 evidence226 SNPs0 traits0 studies0 positive · 1 negative

CASC15

cancer susceptibility 15

This gene produces a long non-coding RNA that may regulate cell proliferation. This RNA is upregulated in hepatocellular carcinoma, where it is thought to function as an oncogen...

3 evidence193 SNPs0 traits0 studies2 positive · 1 negative

AFF3

ALF transcription elongation factor 3

This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly...

1 evidence178 SNPs0 traits0 studies0 positive · 1 negative

Connected SNPs (86)

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