Brain Volume

8K24413

Brain volume is your brain’s physical footprint—measuring the total size of the organ that governs thought, emotion, and behavior, and offering clues about development, aging, and neurological health. Research shows that variations near genes involved in neurodevelopment and cell growth (like HMGA2, MAPT, and KIAA0586...

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SNP Stats

Mapped
244
Positive
125 (51.2%)
Negative
119 (48.8%)

Genome Matching (1)

Public Results (7,973)

5936.4398

OpenSNP · European · Human

25 of 244 SNPs with zeta at 7.034

99.9

4399.2999

OpenSNP · European · Human

26 of 244 SNPs with zeta at 7.034

99.9

6213.4718

OpenSNP · European · Human

25 of 244 SNPs with zeta at 7.034

99.9

7354.5711

OpenSNP · European · Human

26 of 244 SNPs with zeta at 7.034

99.9

6257.4754

OpenSNP · European American · Human

25 of 244 SNPs with zeta at 7.034

99.9

3313.2153

OpenSNP · European · Human

26 of 244 SNPs with zeta at 7.034

99.9

huDD1522

Personal Genome Project · European · Human

26 of 244 SNPs with zeta at 7.013

99.9

Connected Traits (1)

brain volume

OBA_2050009

0 evidence253 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (3)

An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.

PubMed 33875891

0 evidence811 SNPs9 traits1 studies0 positive · 0 negative

Common genetic variants influence human subcortical brain structures.

PubMed 25607358

0 evidence8 SNPs5 traits1 studies0 positive · 0 negative

Common genetic variants have associations with human cortical brain regions and risk of schizophrenia.

PubMed 30941828

0 evidence2 SNPs2 traits1 studies0 positive · 0 negative

Connected Genes (107)

DCC

DCC netrin 1 receptor

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal...

3 evidence268 SNPs0 traits0 studies2 positive · 1 negative

ASTN2

astrotactin 2

This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mou...

4 evidence212 SNPs0 traits0 studies4 positive · 0 negative

HDAC9

histone deacetylase 9

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and...

1 evidence197 SNPs0 traits0 studies1 positive · 0 negative

DLG2

discs large MAGUK scaffold protein 2

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at...

1 evidence194 SNPs0 traits0 studies0 positive · 1 negative

MACROD2

mono-ADP ribosylhydrolase 2

The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the...

2 evidence194 SNPs0 traits0 studies1 positive · 1 negative

Connected SNPs (244)

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