Cannabis Use

8K4215

Cannabis use is a behavioral trait capturing whether—and how often—someone consumes cannabis, shaped by social context, personal preference, and neurobiological sensitivity. Research shows that variations near genes involved in reward processing, impulse control, and cannabinoid signaling (like CADM2, NCAM1, and CNR1)...

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SNP Stats

Mapped
42
Positive
34 (81.0%)
Negative
8 (19.0%)

Genome Matching (1)

Public Results (7,973)

huF8AEC7

Personal Genome Project · European · Human

9 of 42 SNPs with zeta at 7.034

99.9

huE9B698

Personal Genome Project · European · Human

9 of 42 SNPs with zeta at 7.034

99.9

huE07725

Personal Genome Project · American European · Human

8 of 42 SNPs with zeta at 7.034

99.9

huDD5F9B

Personal Genome Project · European · Human

8 of 42 SNPs with zeta at 7.034

99.9

huCFD853

Personal Genome Project · European · Human

8 of 42 SNPs with zeta at 7.034

99.9

huC5263A

Personal Genome Project · European American · Human

9 of 42 SNPs with zeta at 7.034

99.9

huBBEB5D

Personal Genome Project · European · Human

8 of 42 SNPs with zeta at 7.034

99.9

Connected Traits (1)

cannabis use

EFO_0007585

0 evidence42 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (5)

Heritability, SNP- and Gene-Based Analyses of Cannabis Use Initiation and Age at Onset.

PubMed 25987507

0 evidence23 SNPs3 traits1 studies0 positive · 0 negative

Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality.

PubMed 30610198

0 evidence16 SNPs2 traits1 studies0 positive · 0 negative

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.

PubMed 30150663

0 evidence8 SNPs1 traits1 studies0 positive · 0 negative

Connected Genes (22)

CADM2

cell adhesion molecule 2

This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like d...

3 evidence319 SNPs0 traits0 studies2 positive · 1 negative

HLA-B

major histocompatibility complex, class I, B

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy c...

1 evidence227 SNPs0 traits0 studies0 positive · 1 negative

SDK1

sidekick cell adhesion molecule 1

The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains six immunoglobulin-like domains and thirteen fibronectin type III domains. F...

1 evidence205 SNPs0 traits0 studies1 positive · 0 negative

SEMA6D

semaphorin 6D

Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding...

1 evidence179 SNPs0 traits0 studies1 positive · 0 negative

CAST

calpastatin

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhi...

1 evidence168 SNPs0 traits0 studies1 positive · 0 negative

Connected SNPs (42)

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