Cigarettes Per Day Measurement

8K55619

Cigarettes per day measurement quantifies how many cigarettes an individual smokes daily—a key indicator of nicotine dependence and smoking behavior intensity. Research shows that variations near genes involved in nicotine metabolism and neural reward pathways (like CHRNA5, CYP2A6, and DRD2) can influence how much a p...

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SNP Stats

Mapped
556
Positive
291 (52.3%)
Negative
265 (47.7%)

Genome Matching (1)

Public Results (7,972)

HG01110

1000 Genomes Project · European American · Human

498 of 555 SNPs with zeta at 7.034

99.9

HG01707

1000 Genomes Project · European · Human

498 of 555 SNPs with zeta at 7.034

99.9

5329.3841

OpenSNP · American European · Human

56 of 555 SNPs with zeta at 7.034

99.9

HG01670

1000 Genomes Project · European · Human

498 of 555 SNPs with zeta at 7.034

99.9

9600.7898

OpenSNP · European · Human

54 of 555 SNPs with zeta at 7.034

99.9

9742.7999

OpenSNP · European · Human

53 of 555 SNPs with zeta at 7.034

99.9

HG00327

1000 Genomes Project · European · Human

498 of 555 SNPs with zeta at 7.034

99.9

Connected Traits (1)

cigarettes per day measurement

EFO_0006525

0 evidence573 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (9)

Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.

PubMed 39024449

0 evidence15K SNPs829 traits1 studies0 positive · 0 negative

Genetic diversity fuels gene discovery for tobacco and alcohol use.

PubMed 36477530

0 evidence5K SNPs5 traits1 studies0 positive · 0 negative

Pleiotropic genetic architecture and novel loci for C-reactive protein levels.

PubMed 36376304

0 evidence4K SNPs6 traits1 studies0 positive · 0 negative

Connected Genes (202)

CADM2

cell adhesion molecule 2

This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like d...

19 evidence319 SNPs0 traits0 studies19 positive · 0 negative

PTPRD

protein tyrosine phosphatase receptor type D

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular proce...

1 evidence283 SNPs0 traits0 studies0 positive · 1 negative

AUTS2

activator of transcription and developmental regulator AUTS2

This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders, intellectual disability, and...

2 evidence208 SNPs0 traits0 studies2 positive · 0 negative

PDE4B

phosphodiesterase 4B

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of...

1 evidence204 SNPs0 traits0 studies0 positive · 1 negative

WWOX

WW domain containing oxidoreductase

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function...

1 evidence202 SNPs0 traits0 studies0 positive · 1 negative

Connected SNPs (556)

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