facial wrinkling
HP_0009762
0 evidence25 SNPs1 traits0 studies0 positive · 0 negative
Facial Wrinkling
8K2412
Facial wrinkling is your skin’s natural record of aging and environmental exposure, showing lines and creases formed by years of repeated expressions, sun damage, and collagen breakdown. Research shows that variations near genes involved in skin elasticity and collagen production (like MMP1, ELN, and COL1A1) can influ...
SNP Stats
- Mapped
- 24
- Positive
- 14 (58.3%)
- Negative
- 10 (41.7%)
Genome Matching (1)
Public Results (7,973)
3015.1938
OpenSNP · European American · Human
2 of 25 SNPs
hu1AF744
Personal Genome Project · European American · Human
3 of 24 SNPs with zeta at 7.034
6296.4789
OpenSNP · European · Human
3 of 24 SNPs with zeta at 7.034
6633.5035
OpenSNP · European · Human
3 of 24 SNPs with zeta at 7.034
5721.4197
OpenSNP · European · Human
3 of 24 SNPs with zeta at 7.034
5757.4232
OpenSNP · European · Human
3 of 24 SNPs with zeta at 7.034
4528.3125
OpenSNP · European American · Human
3 of 24 SNPs with zeta at 7.034
Connected Traits (1)
Connected Studies (2)
Facial Wrinkles in Europeans: a Genome-Wide Association Study.
0 evidence18 SNPs1 traits1 studies0 positive · 0 negative
A GWAS identifies novel gene associations with facial skin wrinkling and mole count in Latin-Americans.
0 evidence9 SNPs2 traits1 studies0 positive · 0 negative
Connected Genes (20)
LINGO2
leucine rich repeat and Ig domain containing 2
Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. Predicted to be active in extracellular matrix an...
1 evidence133 SNPs0 traits0 studies0 positive · 1 negative
KAZN
kazrin, periplakin interacting protein
This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desm...
1 evidence123 SNPs0 traits0 studies0 positive · 1 negative
LINC01500
long intergenic non-protein coding RNA 1500
1 evidence91 SNPs0 traits0 studies1 positive · 0 negative
BMP6
bone morphogenetic protein 6
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to...
1 evidence63 SNPs0 traits0 studies1 positive · 0 negative
VAV3
vav guanine nucleotide exchange factor 3
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cyto...
1 evidence61 SNPs0 traits0 studies1 positive · 0 negative