Free Cholesterol Measurement

8K71217

Free Cholesterol Measurement quantifies the unesterified (free) form of cholesterol circulating in the blood, particularly within lipoproteins like HDL and LDL. Unlike esterified cholesterol, this form is directly involved in membrane fluidity and lipid metabolism, offering insight into cellular transport dynamics and...

SNP Stats

Mapped
712
Positive
354 (49.7%)
Negative
358 (50.3%)

Genome Matching (1)

Public Results (7,971)

Connected Traits (1)

free cholesterol measurement

Free cholesterol measurement (EFO_0008591) quantifies the concentration of unesterified cholesterol in blood or tissue samples. It is a lipid trait relevant to membrane biology,...

EFO_0008591

0 evidence772 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (7)

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.

PubMed 35213538

0 evidence3K SNPs53 traits1 studies0 positive · 0 negative

Genome-wide characterization of circulating metabolic biomarkers.

PubMed 38448586

0 evidence2K SNPs116 traits1 studies0 positive · 0 negative

Metabolomic Investigation of Major Depressive Disorder Identifies a Potentially Causal Association With Polyunsaturated Fatty Acids.

PubMed 36764567

0 evidence2K SNPs199 traits1 studies0 positive · 0 negative

Connected Genes (235)

ALDH1A2

aldehyde dehydrogenase 1 family member A2

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyd...

10 evidence433 SNPs0 traits0 studies7 positive · 3 negative

POLR1HASP

POLR1H antisense, pseudogene

2 evidence367 SNPs0 traits0 studies2 positive · 0 negative

TSBP1-AS1

TSBP1 and BTNL2 antisense RNA 1

1 evidence317 SNPs0 traits0 studies0 positive · 1 negative

SIK3

SIK family kinase 3

Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in positive regulation of TORC1 signaling; positive regulati...

3 evidence276 SNPs0 traits0 studies1 positive · 2 negative

HLA-DQA1

major histocompatibility complex, class II, DQ alpha 1

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the mem...

3 evidence261 SNPs0 traits0 studies0 positive · 3 negative

Connected SNPs (712)

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