hippocampal volume
EFO_0005035
0 evidence267 SNPs1 traits0 studies0 positive · 0 negative
Hippocampal Volume
8K264112
Hippocampal volume measures the size of the hippocampus, a brain region crucial for memory formation, spatial navigation, and emotional regulation. Research shows that variations near genes involved in neurodevelopment and synaptic plasticity (like BDNF, APOE, and SORL1) can influence differences in hippocampal size....
SNP Stats
- Mapped
- 264
- Positive
- 138 (52.3%)
- Negative
- 126 (47.7%)
Genome Matching (1)
Public Results (7,972)
7195.5578
OpenSNP · European · Human
24 of 264 SNPs with zeta at 6.678
HG03716
1000 Genomes Project · South Asian · Human
240 of 264 SNPs with zeta at 6.632
9594.7860
OpenSNP · European · Human
25 of 264 SNPs with zeta at 6.556
HG01773
1000 Genomes Project · European · Human
240 of 264 SNPs with zeta at 6.231
8787.7132
OpenSNP · European · Human
25 of 264 SNPs with zeta at 6.204
HG00284
1000 Genomes Project · European · Human
240 of 264 SNPs with zeta at 6.109
HG00368
1000 Genomes Project · European American · Human
240 of 264 SNPs with zeta at 6.006
Connected Traits (1)
Connected Studies (12)
Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset.
0 evidence524 SNPs8 traits1 studies0 positive · 0 negative
Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.
0 evidence314 SNPs11 traits1 studies0 positive · 0 negative
Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
0 evidence125 SNPs5 traits1 studies0 positive · 0 negative
Connected Genes (108)
PTPRD
protein tyrosine phosphatase receptor type D
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular proce...
1 evidence283 SNPs0 traits0 studies0 positive · 1 negative
ASTN2
astrotactin 2
This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mou...
7 evidence212 SNPs0 traits0 studies4 positive · 3 negative
SEMA6D
semaphorin 6D
Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding...
1 evidence179 SNPs0 traits0 studies1 positive · 0 negative
XKR6
XK related 6
Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Predicted to be i...
1 evidence154 SNPs0 traits0 studies0 positive · 1 negative
PARD3B
par-3 family cell polarity regulator beta
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in several processes, including establishment of cell polarity; establishment of centrosome l...
2 evidence112 SNPs0 traits0 studies0 positive · 2 negative