irritability measurement
EFO_0009594
0 evidence67 SNPs1 traits0 studies0 positive · 0 negative
Irritability Measurement
8K6711
Irritability measurement captures how easily and frequently an individual becomes annoyed or frustrated—reflecting emotional sensitivity to stress, discomfort, or social interactions. Research shows that variations near genes involved in emotional regulation and neurotransmitter function (such as SLC6A4, MAOA, and COM...
SNP Stats
- Mapped
- 67
- Positive
- 37 (55.2%)
- Negative
- 30 (44.8%)
Genome Matching (1)
Public Results (7,973)
hu0B13B7
Personal Genome Project · European American · Human
3 of 67 SNPs with zeta at 7.034
HG01747
1000 Genomes Project · European · Human
34 of 67 SNPs with zeta at 5.439
HG01747
1000 Genomes Project · European · Human
59 of 67 SNPs with zeta at 4.320
NA20814
1000 Genomes Project · European · Human
59 of 67 SNPs with zeta at 4.307
NA12340
1000 Genomes Project · European · Human
59 of 67 SNPs with zeta at 4.281
NA12273
1000 Genomes Project · European · Human
59 of 67 SNPs with zeta at 4.068
HG01531
1000 Genomes Project · European · Human
43 of 67 SNPs with zeta at 3.874
Connected Traits (1)
Connected Studies (1)
Item-level analyses reveal genetic heterogeneity in neuroticism.
0 evidence662 SNPs12 traits1 studies0 positive · 0 negative
Connected Genes (38)
CADM2
cell adhesion molecule 2
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like d...
2 evidence319 SNPs0 traits0 studies1 positive · 1 negative
AUTS2
activator of transcription and developmental regulator AUTS2
This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders, intellectual disability, and...
1 evidence208 SNPs0 traits0 studies1 positive · 0 negative
MSRA
methionine sulfoxide reductase A
This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown t...
1 evidence206 SNPs0 traits0 studies1 positive · 0 negative
LINC02210-CRHR1
LINC02210-CRHR1 readthrough
This locus represents naturally occurring readthrough transcription between neighboring genes CRHR1-IT1, CRHR1 intronic transcript 1 (Gene ID: 147081) and CRHR1, corticotropin r...
1 evidence145 SNPs0 traits0 studies1 positive · 0 negative
ZFPM2
zinc finger protein, FOG family member 2
The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family pro...
1 evidence145 SNPs0 traits0 studies1 positive · 0 negative