Mood Instability Measurement

8K8114

Mood instability measurement captures how frequently and intensely an individual’s emotional state fluctuates—ranging from periods of happiness to sudden shifts toward sadness, irritability, or anxiety. Research shows that variations near genes involved in neurotransmitter regulation and emotional processing (such as...

SNP Stats

Mapped
81
Positive
36 (44.4%)
Negative
45 (55.6%)

Genome Matching (1)

Public Results (7,973)

Connected Traits (1)

mood instability measurement

EFO_0008475

0 evidence82 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (4)

Item-level analyses reveal genetic heterogeneity in neuroticism.

PubMed 29500382

0 evidence662 SNPs12 traits1 studies0 positive · 0 negative

The Heidelberg Five personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment.

PubMed 33590662

0 evidence18 SNPs5 traits1 studies0 positive · 0 negative

Genome-wide analysis of emotional lability in adult attention deficit hyperactivity disorder (ADHD).

PubMed 31085060

0 evidence6 SNPs1 traits1 studies0 positive · 0 negative

Connected Genes (45)

CSMD1

CUB and Sushi multiple domains 1

Predicted to act upstream of or within several processes, including learning or memory; mammary gland branching involved in pregnancy; and reproductive structure development. Pr...

1 evidence351 SNPs0 traits0 studies0 positive · 1 negative

DCC

DCC netrin 1 receptor

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal...

4 evidence268 SNPs0 traits0 studies2 positive · 2 negative

LSAMP

limbic system associated membrane protein

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neu...

1 evidence203 SNPs0 traits0 studies0 positive · 1 negative

SOX6

SRY-box transcription factor 6

This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high...

1 evidence194 SNPs0 traits0 studies1 positive · 0 negative

RABGAP1L

RAB GTPase activating protein 1 like

Enables GTPase activator activity and small GTPase binding activity. Acts upstream of or within regulation of protein localization. Located in Golgi apparatus; early endosome; a...

1 evidence164 SNPs0 traits0 studies0 positive · 1 negative

Connected SNPs (81)

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