Myopia

8K31315

Myopia, commonly known as nearsightedness, is your eye’s tendency to pull the world in too close—making distant objects blur as if seen through a soft-focus lens. While it can feel like a minor daily hurdle, it’s also a reminder that the shape and growth of your eyeball are finely tuned by both nature and nurture, guid...

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SNP Stats

Mapped
313
Positive
157 (50.2%)
Negative
156 (49.8%)

Genome Matching (1)

Public Results (7,970)

7634.5980

OpenSNP · European · Human

50 of 312 SNPs with zeta at 5.249

99.9

9283.7605

OpenSNP · European · Human

60 of 312 SNPs with zeta at 4.918

99.9

1625.923

OpenSNP · European · Human

36 of 312 SNPs with zeta at 4.870

99.9

6396.4886

OpenSNP · European American · Human

50 of 312 SNPs with zeta at 4.582

99.9

6842.5223

OpenSNP · European · Human

34 of 312 SNPs with zeta at 4.107

99.9

6780.5167

OpenSNP · European · Human

57 of 312 SNPs with zeta at 4.094

99.9

3395.2208

OpenSNP · European · Human

57 of 312 SNPs with zeta at 4.080

99.9

Connected Traits (1)

myopia

HP_0000545

0 evidence317 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (5)

Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.

PubMed 39024449

0 evidence15K SNPs829 traits1 studies0 positive · 0 negative

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.

PubMed 29808027

0 evidence240 SNPs3 traits1 studies0 positive · 0 negative

Genome-wide association meta-analysis of 88,250 individuals highlights pleiotropic mechanisms of five ocular diseases in UK Biobank.

PubMed 35841873

0 evidence78 SNPs5 traits1 studies0 positive · 0 negative

Connected Genes (150)

RBFOX1

RNA binding fox-1 homolog 1

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regul...

5 evidence409 SNPs0 traits0 studies1 positive · 4 negative

CDH13

cadherin 13

This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a tr...

1 evidence226 SNPs0 traits0 studies1 positive · 0 negative

FAM13A

family with sequence similarity 13 member A

Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytosol. Implicate...

1 evidence201 SNPs0 traits0 studies1 positive · 0 negative

DLG2

discs large MAGUK scaffold protein 2

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at...

1 evidence194 SNPs0 traits0 studies0 positive · 1 negative

CASC15

cancer susceptibility 15

This gene produces a long non-coding RNA that may regulate cell proliferation. This RNA is upregulated in hepatocellular carcinoma, where it is thought to function as an oncogen...

4 evidence193 SNPs0 traits0 studies0 positive · 4 negative

Connected SNPs (313)

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