puberty onset measurement
EFO_0005677
0 evidence162 SNPs1 traits0 studies0 positive · 0 negative
Puberty Onset Measurement
8K15513
Puberty onset measurement captures the age at which an individual begins the biological transition from childhood to adolescence, marked by physical and hormonal changes. Research shows that variations near genes involved in hormonal regulation and reproductive development (like LIN28B, KISS1, and MKRN3) can influence...
SNP Stats
- Mapped
- 155
- Positive
- 94 (60.6%)
- Negative
- 61 (39.4%)
Genome Matching (1)
Public Results (7,973)
9036.7374
OpenSNP · European · Human
33 of 155 SNPs with zeta at 3.892
9111.7452
OpenSNP · European · Human
41 of 155 SNPs with zeta at 3.825
3869.2578
OpenSNP · European · Human
28 of 155 SNPs with zeta at 3.800
9081.7421
OpenSNP · European American · Human
41 of 155 SNPs with zeta at 3.649
6221.4725
OpenSNP · European · Human
33 of 155 SNPs with zeta at 3.602
8539.6936
OpenSNP · European American · Human
41 of 155 SNPs with zeta at 3.562
8219.6559
OpenSNP · European American · Human
40 of 155 SNPs with zeta at 3.443
Connected Traits (1)
Connected Studies (3)
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.
0 evidence117 SNPs1 traits1 studies0 positive · 0 negative
Joint models reveal genetic architecture of pubertal stage transitions and their association with BMI in admixed Chilean population.
0 evidence40 SNPs1 traits1 studies0 positive · 0 negative
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.
0 evidence5 SNPs1 traits1 studies0 positive · 0 negative
Connected Genes (80)
RBFOX1
RNA binding fox-1 homolog 1
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regul...
1 evidence409 SNPs0 traits0 studies0 positive · 1 negative
LSAMP
limbic system associated membrane protein
This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neu...
1 evidence203 SNPs0 traits0 studies0 positive · 1 negative
SOX6
SRY-box transcription factor 6
This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high...
1 evidence194 SNPs0 traits0 studies1 positive · 0 negative
JMJD1C
jumonji domain containing 1C
The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator...
1 evidence189 SNPs0 traits0 studies1 positive · 0 negative
RORA
RAR related orphan receptor A
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream...
1 evidence166 SNPs0 traits0 studies1 positive · 0 negative