Reading and Spelling Ability

8K9214

Reading and spelling ability measures your skill in recognizing written words and accurately producing their written forms—key components of literacy development. Research shows that variations near genes involved in language processing and neural development (such as DCDC2, KIAA0319, and FOXP2) can influence individu...

SNP Stats

Mapped
92
Positive
52 (56.5%)
Negative
40 (43.5%)

Genome Matching (1)

Public Results (7,972)

Connected Traits (1)

reading and spelling ability

EFO_0005301

0 evidence96 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (4)

Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.

PubMed 35998220

0 evidence161 SNPs5 traits1 studies0 positive · 0 negative

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia.

PubMed 30741946

0 evidence121 SNPs4 traits1 studies0 positive · 0 negative

A genome-wide association study for reading and language abilities in two population cohorts.

PubMed 23738518

0 evidence16 SNPs3 traits1 studies0 positive · 0 negative

Connected Genes (56)

CADM2

cell adhesion molecule 2

This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like d...

1 evidence319 SNPs0 traits0 studies1 positive · 0 negative

CDH13

cadherin 13

This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a tr...

1 evidence226 SNPs0 traits0 studies1 positive · 0 negative

NRXN1

neurexin 1

This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent...

1 evidence204 SNPs0 traits0 studies1 positive · 0 negative

SEMA6D

semaphorin 6D

Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding...

1 evidence179 SNPs0 traits0 studies1 positive · 0 negative

GPC5

glypican 5

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypic...

1 evidence175 SNPs0 traits0 studies1 positive · 0 negative

Connected SNPs (92)

Explore phenotypes in Genodex

Install the app to compare this phenotype with your genomes, inspect private results, and explore the full evidence context.

Download the app