sex interaction measurement
EFO_0008343
0 evidence161 SNPs1 traits0 studies0 positive · 0 negative
Sex Interaction Measurement
8K16116
Sex interaction measurement captures how biological sex influences the effect of genetic variants on traits or diseases—highlighting differences in genetic impact between males and females. Research shows that certain gene-trait associations vary depending on sex, with genes involved in hormone regulation (like ESR1 a...
SNP Stats
- Mapped
- 161
- Positive
- 90 (55.9%)
- Negative
- 71 (44.1%)
Genome Matching (1)
Public Results (7,972)
3941.2641
OpenSNP · European · Human
23 of 161 SNPs with zeta at 7.034
2904.1844
OpenSNP · European · Human
23 of 161 SNPs with zeta at 7.034
3903.2608
OpenSNP · European American · Human
25 of 161 SNPs with zeta at 6.547
HG01058
1000 Genomes Project · European American · Human
143 of 161 SNPs with zeta at 6.263
2729.1736
OpenSNP · European American · Human
23 of 161 SNPs with zeta at 6.234
5269.3779
OpenSNP · European · Human
25 of 161 SNPs with zeta at 6.074
3501.2275
OpenSNP · European · Human
24 of 161 SNPs with zeta at 5.915
Connected Traits (1)
Connected Studies (6)
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.
0 evidence180 SNPs5 traits1 studies0 positive · 0 negative
Gene-Environment Interaction Analysis Incorporating Sex, Cardiometabolic Diseases, and Multiple Deprivation Index Reveals Novel Genetic Associations With COVID-19 Severity.
0 evidence43 SNPs4 traits1 studies0 positive · 0 negative
New insights from GWAS on BMI-related growth traits in a longitudinal cohort of admixed children with Native American and European ancestry.
0 evidence28 SNPs4 traits1 studies0 positive · 0 negative
Connected Genes (84)
LRP1B
LDL receptor related protein 1B
This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to thei...
1 evidence237 SNPs0 traits0 studies1 positive · 0 negative
ERBB4
erb-b2 receptor tyrosine kinase 4
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cystein...
1 evidence219 SNPs0 traits0 studies1 positive · 0 negative
WWOX
WW domain containing oxidoreductase
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function...
1 evidence202 SNPs0 traits0 studies1 positive · 0 negative
DLG2
discs large MAGUK scaffold protein 2
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at...
1 evidence194 SNPs0 traits0 studies1 positive · 0 negative
FHIT
fragile histidine triad diadenosine triphosphatase
The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromos...
2 evidence189 SNPs0 traits0 studies1 positive · 1 negative