Skin Sensitivity to Sun

8K2614

Some people tan golden brown with ease; others burn red within minutes. Our skin's reaction to sunlight isn’t a matter of toughness—it's a deeply wired trait shaped by millennia of adaptation to regional UV exposure. This sensitivity tells a story of ancestral geography, melanin protection, and cellular defense mechani...

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SNP Stats

Mapped
16
Positive
8 (50.0%)
Negative
8 (50.0%)

Genome Matching (1)

Public Results (7,973)

7535.5882

OpenSNP · European American · Human

6 of 16 SNPs with zeta at 6.220

99.9

9284.7606

OpenSNP · European · Human

6 of 16 SNPs with zeta at 5.259

99.9

7630.5978

OpenSNP · European American · Human

6 of 16 SNPs with zeta at 5.259

99.9

8504.6866

OpenSNP · European American · Human

6 of 16 SNPs with zeta at 4.303

99.9

9391.7698

OpenSNP · European American · Human

6 of 16 SNPs with zeta at 4.303

99.9

9039.7382

OpenSNP · European · Human

6 of 16 SNPs with zeta at 4.303

99.9

8957.7298

OpenSNP · European · Human

6 of 16 SNPs with zeta at 4.303

99.9

Connected Traits (1)

skin sensitivity to sun

EFO_0004795

0 evidence57 SNPs1 traits0 studies0 positive · 0 negative

Connected Studies (4)

Skin Phototype and Disease: A Comprehensive Genetic Approach to Pigmentary Traits Pleiotropy Using PRS in the GCAT Cohort.

PubMed 36672889

0 evidence284 SNPs5 traits1 studies0 positive · 0 negative

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up.

PubMed 25963972

0 evidence11 SNPs2 traits1 studies0 positive · 0 negative

Genetic determinants of hair, eye and skin pigmentation in Europeans.

PubMed 17952075

0 evidence7 SNPs4 traits1 studies0 positive · 0 negative

Connected Genes (3)

FANCA

FA complementation group A

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1)...

1 evidence61 SNPs0 traits0 studies0 positive · 1 negative

ADAMTS12

ADAM metallopeptidase with thrombospondin type 1 motif 12

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein mo...

1 evidence36 SNPs0 traits0 studies0 positive · 1 negative

SLC45A2

solute carrier family 45 member 2

This gene encodes a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause...

5 evidence29 SNPs0 traits0 studies1 positive · 4 negative

Connected SNPs (16)

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