Netherlands

Genome of the NetherlandsEuropean

This reference genome is built from the Genome of the Netherlands (GoNL) Release 5, registered under PRJEB5829, based on whole-genome sequencing of Dutch parent–offspring families sampled nationwide under BBMRI-NL. Dutch genomes cluster within Northwestern Europe with subtle north–south and east–west clines; the Release 5 reference set includes 998 unrelated haplotypes widely used for imputation and Dutch-specific allele-frequency baselines. Here we collapse the study-wide SNP allele counts into a per-locus consensus genotype baseline and use it as a comparative anchor across populations.

Basic Information

Genodex Edge

Phenotypes (120)

Handedness

60 of 86 SNPs with zeta at 7.034

99.9

Pain Perception

39 of 42 SNPs with zeta at 7.034

99.9

Protein Measurement

4,509 of 5,497 SNPs with zeta at 5.386

99.9

Drug Use Measurement

313 of 390 SNPs with zeta at 3.385

99.9

Freckles

14 of 15 SNPs with zeta at 2.917

99.8

Alcohol Drinking

52 of 61 SNPs with zeta at 2.765

99.7

Coffee Consumption Measurement

173 of 187 SNPs with zeta at 2.454

99.3

Response to Reward

24 of 27 SNPs with zeta at 2.353

99.1

Physical Activity Measurement

312 of 332 SNPs with zeta at 2.323

99.0

Smoking Behavior

408 of 423 SNPs with zeta at 2.096

98.2

Language Measurement

97 of 114 SNPs with zeta at 1.971

97.6

Anxiety Measurement

157 of 169 SNPs with zeta at 1.959

97.5

Head Circumference

14 of 16 SNPs with zeta at 1.952

97.5

Facial Emotion Recognition Measurement

23 of 24 SNPs with zeta at 1.951

97.4

Executive Function Measurement

112 of 129 SNPs with zeta at 1.870

96.9

Age at First Sexual Intercourse

201 of 235 SNPs with zeta at 1.778

96.2

Skin Sensitivity to Sun

15 of 16 SNPs with zeta at 1.667

95.2

Lean Body Mass

923 of 1,053 SNPs with zeta at 1.489

93.2

Height Growth Attribute

111 of 196 SNPs with zeta at 1.484

93.1

Waist-hip Ratio

577 of 645 SNPs with zeta at 1.390

91.8

Systolic Blood Pressure

4,275 of 4,722 SNPs with zeta at 1.382

91.6

Suntan

73 of 82 SNPs with zeta at 1.304

90.4

Back Pain

70 of 81 SNPs with zeta at 1.285

90.1

Dental Caries

134 of 159 SNPs with zeta at 1.211

88.7

Sweet Liking Measurement

25 of 29 SNPs with zeta at 1.209

88.7

Diastolic Blood Pressure

3,589 of 3,958 SNPs with zeta at 1.169

87.9

Body Height

22,686 of 25,094 SNPs with zeta at 1.167

87.8

Feeling Miserable Measurement

60 of 64 SNPs with zeta at 1.154

87.6

Memory Performance

347 of 386 SNPs with zeta at 1.136

87.2

Hair Color

162 of 185 SNPs with zeta at 1.116

86.8

Facial Wrinkling

22 of 24 SNPs with zeta at 1.052

85.4

Hip Circumference

320 of 378 SNPs with zeta at 0.965

83.3

Educational Attainment

7,202 of 7,751 SNPs with zeta at 0.948

82.8

Feeling Nervous Measurement

58 of 65 SNPs with zeta at 0.944

82.8

Restless Legs

335 of 368 SNPs with zeta at 0.915

82.0

Breast Size

34 of 37 SNPs with zeta at 0.893

81.4

BMI-adjusted hip circumference

2,917 of 3,247 SNPs with zeta at 0.876

81.0

Guilt Measurement

26 of 31 SNPs with zeta at 0.866

80.7

Tea Consumption Measurement

98 of 123 SNPs with zeta at 0.854

80.3

Aggressive Behavior

20 of 21 SNPs with zeta at 0.808

79.0

Cigarettes Per Day Measurement

491 of 555 SNPs with zeta at 0.802

78.9

Brain Volume

210 of 244 SNPs with zeta at 0.801

78.8

Waist Circumference

322 of 383 SNPs with zeta at 0.753

77.4

Vitamin D Amount

506 of 584 SNPs with zeta at 0.707

76.0

Intelligence

1,652 of 1,763 SNPs with zeta at 0.701

75.8

Information Processing Speed

90 of 92 SNPs with zeta at 0.670

74.9

Brain Physiology Trait

98 of 105 SNPs with zeta at 0.641

73.9

Social Communication Impairment

21 of 21 SNPs with zeta at 0.619

73.2

Mathematical Ability

2,133 of 2,298 SNPs with zeta at 0.595

72.4

Reading and Spelling Ability

85 of 92 SNPs with zeta at 0.549

70.9

Breastfeeding Duration

2,343 of 2,455 SNPs with zeta at 0.545

70.7

Loneliness Measurement

27 of 29 SNPs with zeta at 0.515

69.7

Vitamin B12 Measurement

35 of 41 SNPs with zeta at 0.510

69.5

Motion Sickness

34 of 35 SNPs with zeta at 0.490

68.8

Fish Consumption

45 of 51 SNPs with zeta at 0.459

67.7

BMI-adjusted Waist Circumference

2,465 of 2,771 SNPs with zeta at 0.388

65.1

Non-word Reading

38 of 43 SNPs with zeta at 0.365

64.3

Sleep Duration Trait

276 of 306 SNPs with zeta at 0.320

62.6

BMI-adjusted Waist-hip Ratio

2,881 of 3,185 SNPs with zeta at 0.264

60.4

Empathy Measurement

90 of 102 SNPs with zeta at 0.177

57.0

Appendicular Lean Mass

907 of 1,068 SNPs with zeta at 0.156

56.2

Hippocampal Volume

235 of 264 SNPs with zeta at 0.147

55.9

Aggressive Behavior Quality

79 of 82 SNPs with zeta at 0.110

54.4

Body Mass Index

8,331 of 9,015 SNPs with zeta at 0.106

54.2

Vital Capacity

501 of 558 SNPs with zeta at 0.084

53.3

Word Reading

88 of 92 SNPs with zeta at 0.028

51.1

Heart Rate

647 of 712 SNPs with zeta at 0.018

50.7

Feeling fed-up measurement

54 of 60 SNPs with zeta at -0.048

48.1

Daytime Rest Measurement

181 of 199 SNPs with zeta at -0.123

45.1

Feeling Emotionally Hurt Measurement

44 of 46 SNPs with zeta at -0.151

44.0

Cognitive Function Measurement

1,126 of 1,231 SNPs with zeta at -0.170

43.2

Sexual Activity Behavior Attribute

147 of 158 SNPs with zeta at -0.188

42.5

Balding measurement

615 of 667 SNPs with zeta at -0.191

42.4

Total Cholesterol Measurement

2,816 of 3,245 SNPs with zeta at -0.210

41.7

Myopia

278 of 312 SNPs with zeta at -0.212

41.6

Brain Attribute

756 of 838 SNPs with zeta at -0.237

40.6

Sex Interaction Measurement

146 of 161 SNPs with zeta at -0.272

39.3

Risk Taking Behavior

582 of 626 SNPs with zeta at -0.303

38.1

Cannabis Dependence

29 of 29 SNPs with zeta at -0.333

36.9

Response to exercise

47 of 57 SNPs with zeta at -0.347

36.4

Energy Intake

78 of 87 SNPs with zeta at -0.359

36.0

Body Fat Percentage

514 of 599 SNPs with zeta at -0.368

35.6

Taste Liking Measurement

445 of 526 SNPs with zeta at -0.403

34.3

Free Cholesterol Measurement

624 of 712 SNPs with zeta at -0.412

34.0

Blood Protein Measurement

394 of 467 SNPs with zeta at -0.455

32.4

Puberty Onset Measurement

136 of 155 SNPs with zeta at -0.456

32.4

Acne

117 of 123 SNPs with zeta at -0.476

31.7

Neuroticism Measurement

1,460 of 1,570 SNPs with zeta at -0.478

31.6

Worry Measurement

110 of 116 SNPs with zeta at -0.482

31.5

Hypermetropia

27 of 29 SNPs with zeta at -0.500

30.8

Household Income

368 of 383 SNPs with zeta at -0.501

30.8

Growth Rate Attribute

96 of 142 SNPs with zeta at -0.532

29.7

Sugar Consumption Measurement

75 of 78 SNPs with zeta at -0.544

29.3

Seasonal Allergic Rhinitis

50 of 55 SNPs with zeta at -0.547

29.2

Social Interaction Measurement

55 of 59 SNPs with zeta at -0.549

29.1

Word List Delayed Recall Measurement

17 of 17 SNPs with zeta at -0.600

27.4

Creatine Measurement

29 of 32 SNPs with zeta at -0.603

27.3

Irritability Measurement

64 of 67 SNPs with zeta at -0.612

27.0

Attention Function Measurement

89 of 97 SNPs with zeta at -0.624

26.6

Body Fat Distribution

166 of 180 SNPs with zeta at -0.631

26.4

Aging Rate

114 of 123 SNPs with zeta at -0.656

25.6

Alcohol Consumption Quality

1,646 of 1,832 SNPs with zeta at -0.664

25.3

Hearing Loss

42 of 53 SNPs with zeta at -0.708

24.0

Feeling Tense Measurement

32 of 33 SNPs with zeta at -0.714

23.8

Creativity Measurement

54 of 61 SNPs with zeta at -0.806

21.0

Mood Instability Measurement

77 of 81 SNPs with zeta at -0.884

18.8

Short Term Memory

163 of 174 SNPs with zeta at -1.055

14.6

Phoneme Awareness

53 of 58 SNPs with zeta at -1.065

14.3

Social Inhibition Quality

531 of 574 SNPs with zeta at -1.066

14.3

Insomnia

2,515 of 2,710 SNPs with zeta at -1.086

13.9

Brain Connectivity Attribute

290 of 329 SNPs with zeta at -1.260

10.4

Age at Menopause

191 of 209 SNPs with zeta at -1.271

10.2

Astigmatism

81 of 86 SNPs with zeta at -1.405

8.0

Eye Color

92 of 103 SNPs with zeta at -1.549

6.1

Skin Pigmentation

210 of 244 SNPs with zeta at -1.567

5.9

Behavioral Disinhibition Measurement

120 of 134 SNPs with zeta at -1.798

3.6

Cannabis Use

41 of 42 SNPs with zeta at -2.343

1.0

Sex hormone-binding globulin

1,519 of 1,793 SNPs with zeta at -2.754

0.3

Circadian Rhythm

45 of 54 SNPs with zeta at -3.649

0.0

Sleep Quality

114 of 140 SNPs with zeta at -5.789

0.0

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