Middle Eastern

gnomADEuropean

This reference genome is built from the gnomAD v4 — Genomes Middle Eastern (MID) ancestry group, registered under PRJNA398795, aggregating short-read WGS from ~294 individuals assigned to the MID genetic-ancestry cluster. Middle Eastern cohorts display clinal structure across the Levant, Arabian Peninsula, North Africa, and the Iranian Plateau, with elevated runs of homozygosity in more endogamous subgroups and allele-frequency gradients bridging Europe, Africa, and South Asia. Here we collapse the study-wide SNP allele counts into a per-locus consensus genotype baseline and use it as a comparative anchor across populations.

Basic Information

Genodex Edge

Phenotypes (120)

Coffee Consumption Measurement

153 of 187 SNPs with zeta at 4.207

99.9

Sex hormone-binding globulin

1,510 of 1,793 SNPs with zeta at 3.673

99.9

Circadian Rhythm

42 of 54 SNPs with zeta at 2.810

99.8

Sleep Duration Trait

255 of 306 SNPs with zeta at 2.618

99.6

Alcohol Consumption Quality

1,525 of 1,832 SNPs with zeta at 2.597

99.5

Waist Circumference

307 of 383 SNPs with zeta at 2.188

98.6

Free Cholesterol Measurement

590 of 712 SNPs with zeta at 1.822

96.6

Vitamin B12 Measurement

36 of 41 SNPs with zeta at 1.715

95.7

Skin Sensitivity to Sun

14 of 16 SNPs with zeta at 1.667

95.2

Intelligence

1,485 of 1,763 SNPs with zeta at 1.607

94.6

Back Pain

70 of 81 SNPs with zeta at 1.597

94.5

Smoking Behavior

361 of 423 SNPs with zeta at 1.583

94.3

Total Cholesterol Measurement

2,749 of 3,245 SNPs with zeta at 1.439

92.5

Aggressive Behavior Quality

71 of 82 SNPs with zeta at 1.407

92.0

Vitamin D Amount

485 of 584 SNPs with zeta at 1.395

91.9

Facial Wrinkling

19 of 24 SNPs with zeta at 1.353

91.2

Protein Measurement

4,722 of 5,497 SNPs with zeta at 1.266

89.7

Behavioral Disinhibition Measurement

115 of 134 SNPs with zeta at 1.266

89.7

Executive Function Measurement

107 of 129 SNPs with zeta at 1.257

89.6

Language Measurement

99 of 114 SNPs with zeta at 1.186

88.2

Sleep Quality

111 of 140 SNPs with zeta at 1.182

88.1

Guilt Measurement

23 of 31 SNPs with zeta at 1.135

87.2

Waist-hip Ratio

539 of 645 SNPs with zeta at 1.130

87.1

Memory Performance

304 of 386 SNPs with zeta at 1.126

87.0

Lean Body Mass

871 of 1,053 SNPs with zeta at 1.070

85.8

Aggressive Behavior

18 of 21 SNPs with zeta at 1.000

84.1

Body Height

20,958 of 25,094 SNPs with zeta at 0.963

83.2

Word Reading

81 of 92 SNPs with zeta at 0.960

83.2

Dental Caries

132 of 159 SNPs with zeta at 0.913

81.9

Height Growth Attribute

165 of 196 SNPs with zeta at 0.877

81.0

Growth Rate Attribute

111 of 142 SNPs with zeta at 0.847

80.1

Sweet Liking Measurement

25 of 29 SNPs with zeta at 0.813

79.2

Balding measurement

576 of 667 SNPs with zeta at 0.761

77.7

BMI-adjusted Waist Circumference

2,277 of 2,771 SNPs with zeta at 0.721

76.4

Short Term Memory

152 of 174 SNPs with zeta at 0.683

75.3

Feeling Nervous Measurement

53 of 65 SNPs with zeta at 0.648

74.1

Hearing Loss

42 of 53 SNPs with zeta at 0.574

71.7

Anxiety Measurement

151 of 169 SNPs with zeta at 0.573

71.7

Physical Activity Measurement

277 of 332 SNPs with zeta at 0.547

70.8

Information Processing Speed

85 of 92 SNPs with zeta at 0.542

70.6

Breastfeeding Duration

2,066 of 2,455 SNPs with zeta at 0.525

70.0

Feeling Emotionally Hurt Measurement

39 of 46 SNPs with zeta at 0.481

68.5

Motion Sickness

32 of 35 SNPs with zeta at 0.470

68.1

Hip Circumference

315 of 378 SNPs with zeta at 0.458

67.7

Educational Attainment

6,558 of 7,751 SNPs with zeta at 0.446

67.2

BMI-adjusted hip circumference

2,725 of 3,247 SNPs with zeta at 0.441

67.0

Reading and Spelling Ability

75 of 92 SNPs with zeta at 0.434

66.8

Brain Connectivity Attribute

269 of 329 SNPs with zeta at 0.421

66.3

Social Communication Impairment

18 of 21 SNPs with zeta at 0.333

63.1

Cannabis Dependence

25 of 29 SNPs with zeta at 0.333

63.1

Empathy Measurement

81 of 102 SNPs with zeta at 0.333

63.0

Drug Use Measurement

336 of 390 SNPs with zeta at 0.301

61.8

Body Mass Index

7,646 of 9,015 SNPs with zeta at 0.280

61.0

Brain Volume

197 of 244 SNPs with zeta at 0.272

60.7

Feeling Miserable Measurement

54 of 64 SNPs with zeta at 0.219

58.7

Pain Perception

38 of 42 SNPs with zeta at 0.200

57.9

Hypermetropia

28 of 29 SNPs with zeta at 0.170

56.8

Response to exercise

46 of 57 SNPs with zeta at 0.161

56.4

Feeling Tense Measurement

30 of 33 SNPs with zeta at 0.145

55.8

Sex Interaction Measurement

137 of 161 SNPs with zeta at 0.142

55.7

Body Fat Percentage

498 of 599 SNPs with zeta at 0.136

55.4

Vital Capacity

475 of 558 SNPs with zeta at 0.130

55.2

Alcohol Drinking

51 of 61 SNPs with zeta at 0.116

54.6

Brain Physiology Trait

85 of 105 SNPs with zeta at 0.090

53.6

Age at First Sexual Intercourse

196 of 235 SNPs with zeta at 0.057

52.3

Skin Pigmentation

202 of 244 SNPs with zeta at 0.042

51.7

Breast Size

31 of 37 SNPs with zeta at 0.042

51.7

Risk Taking Behavior

534 of 626 SNPs with zeta at -0.020

49.2

Response to Reward

24 of 27 SNPs with zeta at -0.027

48.9

Seasonal Allergic Rhinitis

44 of 55 SNPs with zeta at -0.030

48.8

Sexual Activity Behavior Attribute

144 of 158 SNPs with zeta at -0.043

48.3

Handedness

70 of 86 SNPs with zeta at -0.077

46.9

Worry Measurement

102 of 116 SNPs with zeta at -0.089

46.4

Hair Color

153 of 185 SNPs with zeta at -0.107

45.8

Attention Function Measurement

82 of 97 SNPs with zeta at -0.152

44.0

Diastolic Blood Pressure

3,349 of 3,958 SNPs with zeta at -0.159

43.7

Loneliness Measurement

23 of 29 SNPs with zeta at -0.177

43.0

Cognitive Function Measurement

1,051 of 1,231 SNPs with zeta at -0.186

42.6

Word List Delayed Recall Measurement

14 of 17 SNPs with zeta at -0.191

42.4

Eye Color

91 of 103 SNPs with zeta at -0.201

42.0

Suntan

66 of 82 SNPs with zeta at -0.215

41.5

Energy Intake

80 of 87 SNPs with zeta at -0.249

40.2

Freckles

13 of 15 SNPs with zeta at -0.250

40.1

Facial Emotion Recognition Measurement

18 of 24 SNPs with zeta at -0.267

39.5

Social Inhibition Quality

480 of 574 SNPs with zeta at -0.286

38.7

Creatine Measurement

28 of 32 SNPs with zeta at -0.378

35.3

Acne

104 of 123 SNPs with zeta at -0.379

35.2

Tea Consumption Measurement

103 of 123 SNPs with zeta at -0.458

32.3

Aging Rate

106 of 123 SNPs with zeta at -0.474

31.8

Household Income

326 of 383 SNPs with zeta at -0.537

29.6

Restless Legs

314 of 368 SNPs with zeta at -0.537

29.6

Neuroticism Measurement

1,318 of 1,570 SNPs with zeta at -0.792

21.4

Brain Attribute

703 of 838 SNPs with zeta at -0.792

21.4

Myopia

265 of 312 SNPs with zeta at -0.887

18.8

Insomnia

2,307 of 2,710 SNPs with zeta at -0.891

18.6

BMI-adjusted Waist-hip Ratio

2,649 of 3,185 SNPs with zeta at -0.919

17.9

Fish Consumption

40 of 51 SNPs with zeta at -0.920

17.9

Cannabis Use

36 of 42 SNPs with zeta at -0.978

16.4

Head Circumference

16 of 16 SNPs with zeta at -1.000

15.9

Astigmatism

74 of 86 SNPs with zeta at -1.019

15.4

Body Fat Distribution

144 of 180 SNPs with zeta at -1.048

14.7

Irritability Measurement

54 of 67 SNPs with zeta at -1.062

14.4

Phoneme Awareness

52 of 58 SNPs with zeta at -1.067

14.3

Mood Instability Measurement

73 of 81 SNPs with zeta at -1.073

14.2

Cigarettes Per Day Measurement

455 of 555 SNPs with zeta at -1.103

13.5

Appendicular Lean Mass

875 of 1,068 SNPs with zeta at -1.122

13.1

Mathematical Ability

1,940 of 2,298 SNPs with zeta at -1.123

13.1

Non-word Reading

37 of 43 SNPs with zeta at -1.311

9.5

Systolic Blood Pressure

3,968 of 4,722 SNPs with zeta at -1.313

9.5

Heart Rate

612 of 712 SNPs with zeta at -1.360

8.7

Hippocampal Volume

218 of 264 SNPs with zeta at -1.391

8.2

Feeling fed-up measurement

46 of 60 SNPs with zeta at -1.420

7.8

Age at Menopause

185 of 209 SNPs with zeta at -1.465

7.1

Social Interaction Measurement

49 of 59 SNPs with zeta at -1.470

7.1

Puberty Onset Measurement

126 of 155 SNPs with zeta at -1.672

4.7

Taste Liking Measurement

440 of 526 SNPs with zeta at -1.755

4.0

Blood Protein Measurement

401 of 467 SNPs with zeta at -1.767

3.9

Creativity Measurement

45 of 61 SNPs with zeta at -1.936

2.6

Sugar Consumption Measurement

63 of 78 SNPs with zeta at -2.581

0.5

Daytime Rest Measurement

146 of 199 SNPs with zeta at -3.134

0.1

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